Generation of cytolytic T cells in individuals infected by Mycobacterium tuberculosis and vaccinated with BCG.
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چکیده
منابع مشابه
Generation of cytolytic T cells in individuals infected by Mycobacterium tuberculosis and vaccinated with BCG.
BACKGROUND Macrophage activation by cytokines provides only a partial explanation of antimycobacterial immunity in man. Because cytolytic T lymphocytes have been shown to contribute to immunity in animal models of intracellular infection, the generation of mycobacterial antigen specific cytotoxic T cells was examined in the peripheral blood of patients with tuberculosis. METHODS Subjects comp...
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i
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test, chest X-ray, ESR, biopsy of the lesion whenever available, isolation of AFB if possible, and examination of the spinal, pleural or ascitic fluid depending upon the type of tuberculosis. Tuberculin test was done with 1 TU of purified protein derivative and was considered positive, when after 72 hours, an induration of more than 10 x 10 mm was seen. Presence of BCG scar was taken as confirm...
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ژورنال
عنوان ژورنال: Thorax
سال: 1992
ISSN: 0040-6376
DOI: 10.1136/thx.47.9.695